The ability of a country to quickly implement early screening and detection of COVID-19 cases has proven key to effectively managing the spread of the disease. But the scale and speed of infection has posed serious challenges to many governments.
In order to address these challenges BGI, in collaboration with the company Etopia, have jointly designed a mobile, inflatable P2 level biosafety laboratory, the Huo-Yan Air Lab, which enables partners to rapidly deploy and implement a professional, in-country diagnostic laboratory solution for COVID-19. The Huo-Yan Air Lab was unveiled GeneBank on April 3, 2020. The biological nucleic acid “Huo-Yan” Air Lab laboratory is designed for the screening and testing of SARS-CoV-2. The Huo-Yan Air Lab uses a modular air dome structure. It can be easily transported by air as standard freight on any commercial passenger plan, and quickly constructed and safely deployed allowing authorities to control the pandemic at an earlier stage. A P3 level biosafety laboratory was constructed using an inflatable structure during the Ebola outbreak in 2014 in West Africa, where BGI contributed to the response efforts and helped to develop virus detection kits.. The lab covers an area of about 400 square meters and is designed to process from 5,000 to 10,000 samples per day.
The design of Huo-Yan Air Lab consists of five major functional areas: Sample Collection, Sample Reception, Sample Preparation, Reagent Preparation and Amplification. The Huo-Yan Air Lab is equipped with auxiliary conversion space, including air lock conversion and medical waste exhaust system, and is installed with Class II biological safety cabinets, automatic nucleic acid preparation instruments, qPCR instruments, antibody detection equipment, gene sequencers, high-performance servers and other COVID-19 virus nucleic acid detection equipment. The laboratory is designed with a fresh air system and High Efficiency Particulate Air Filter (HEPA) to independently filter and manage the air entering and exiting the air in each functional area. This ensures that the gases in each functional space do not contaminate each other, and at the same time guarantees that outward emissions are correctly and safely filtered to comply with relevant standards and guidelines for biological safety in gene amplification laboratories and virus detection laboratories.